hrp0089p2-p288 | Multisystem Endocrine Disorders P2 | ESPE2018

Can Oral Iron Chelation Therapies Reduce Endocrine Complications in β-Thalassemia Major Patients?

Rostami Parastoo , Mohsenipour Reyhaneh , Khoshkbarforoshan Mina , Sayarifard Fatemeh , Setoudeh Arya , Safari Alieh , Kompani Farzad

Objective: β-thalassemia major is an autosomal recessive hemoglobinopathy that needs to blood transfusion for the survival of patients with β-thalassemia. Iron overload as a side effect of transfusion causes some endocrine deficiency in these patients. The injectable iron chelators as an only treatment in the past lead to painful among patients. At present, use of oral iron chelator and increase in patients’ compliance has been successful....